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15 de jun. de 2023 · Among adults with coma who are resuscitated after out-of-hospital cardiac arrest, observational studies and a phase 2 trial 16,17,19 have shown an association between mild hypercapnia in the first ...
In this multicentre, randomised, double-blind, placebo-controlled trial, adults (≥18 years) with S aureus bacteraemia who had received ≤96 h of active antibiotic therapy were recruited from 29 UK hospitals. Patients were randomly assigned (1:1) via a computer-generated sequential randomisation list to receive 2 weeks of adjunctive rifampicin (600 mg or 900 mg per day according to weight ...
27 de ago. de 2023 · Víctor M. Juárez Olmos ARREST Trial ARREST trial– Expedited transfer to a cardiac arrest centre for non-ST-elevation out-of-hospital cardiac arrest (ARREST) ESC Congress 2023 Presentation Tiffany Patterson Tiffany Patterson et al. The Lancet. 27 Aug 2023 https: ...
4 de mar. de 2021 · Lactic acid > 18 mmol/L. ECMO cannulas placed by cardiologist and perfusion started. Coronary angiography was then completed. Standard ALCS group. Stayed in ED under the care of the emergency physician. Treatment was continued for at least 15 minutes after arrival or at least 60 minutes after 911 call. If ROSC obtained, patient then transferred ...
2 de feb. de 2024 · Cardiac arrest and resuscitation science is advancing rapidly, with the last decade witnessing a surge in the publication of randomised clinical trials (RCT) that can inform guidelines and clinical practice. Several RCTs focusing on temperature control,1–3 post-resuscitation physiological targets,4–6 and treatment of refractory cardiac arrest7,8 were published in 2021 and in 2022, and ...
The ARREST trial will generate safety/effectiveness data and comparative costs associated with extracorporeal cardiopulmonary resuscitation, informing broader implementation and a definitive Phase III clinical trial. Rationale and methods of the Advanced R 2 Eperfusion STrategies for Refractory Cardiac Arrest (ARREST) trial
1 de nov. de 2020 · Clinical equipoise for a randomized trial. Kim et al 31 performed a meta-analysis of studies published through 2015 and concluded that, although rates of survival and good neurologic outcome at 3-6 months after cardiac arrest tended to be higher with ECPR than with conventional CPR in overall analyses, the effects of ECPR were not clear in patients with OHCA.
