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  1. Hace 9 horas · The East–West Schism, also known as the Great Schism or the Schism of 1054, is the break of communion between the Catholic and Eastern Orthodox churches since 1054. [1] A series of ecclesiastical differences and theological disputes between the Greek East and Latin West preceded the formal split that occurred in 1054.

  2. Hace 9 horas · Osteoarthritis (OA) is a degenerative joint disease characterized by the destruction of the articular cartilage, resulting in a pro-inflammatory response. The progression of OA is multifactorial and is influenced by the underlying cause of inflammation, which includes but is not limited to trauma, metabolism, biology, comorbidities, and biomechanics. Although articular cartilage is the main ...