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Hace 9 horas · In this study, we generated new in-vivo treatment models of Brca1- and Bard1-mutant breast cancer that recapitulate the striking response to PARPi, acquired resistance, and recurrence that is observed in patients with breast cancer.Distinct from previously defined resistance mechanisms, we identified a novel PGF-FLT1-AKT signaling pathway of adaptive resistance to PARPi using these models.
Hace 9 horas · As Time Goes By – Craig’s Royal Hotel, Ballarat on July 21. Celebrating music from the 1920s through to the 1960s, the Klemantyne Ensemble will present popular works by Gershwin, Duke Ellington, The Beatles and more. Polaris – Civic Hall, Ballarat on July 21 & Wool Exchange Entertainment Complex, Geelong on July 27.
Hace 9 horas · Background Histone deacetylases (HDACs) and histone acetyltransferases (HATs) are involved in plant growth and development as well as in response to environmental changes, by dynamically regulating gene acetylation levels. Although there have been numerous reports on the identification and function of HDAC and HAT in herbaceous plants, there are fewer report related genes in woody plants under ...
Hace 9 horas · Northeastern Algeria boasts numerous hot springs, yet these hydrothermal sites remain largely unexplored for their microbial ecology. The present study explores the bacterial abundance and diversity within two distinct Algerian hot springs (Hammam Saïda and Hammam Debagh) and investigates the link between the prevailing bacteria with geochemical parameters. High-throughput 16S rRNA gene ...
Hace 9 horas · The following is a list of notable deaths in August 2023 . Entries for each day are listed alphabetically by surname. A typical entry lists information in the following sequence: Name, age, country of citizenship at birth, subsequent country of citizenship (if applicable), reason for notability, cause of death (if known), and reference.
Hace 9 horas · Save this search and receive email when new items match your search criteria. Type. Containers (2741) Excavator Attachments (2549) Excavators (3475) Industrial & Construction (219
Hace 9 horas · Les paris EN DIRECT sont un moyen facile pour parier sur des sports pendant les matchs. 1XBET.COM Bookmaker.
