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James Edwin Darnell Jr. (born September 9, 1930, Columbus, Mississippi) is an American biologist who made significant contributions to RNA processing and cytokine signaling and is author of the cell biology textbook Molecular Cell Biology.
James E. Darnell Jr., M.D. Vincent Astor Professor Emeritus. Laboratory of Molecular Cell Biology. The Darnell laboratory studies how signals from the cell surface affect the transcription of genes in the nucleus.
Biography of James E. Darnell, Jr. from Concept 35: DNA responds to signals from outside the cell, DNA from the Beginning.
Abstract. Several strong conclusions emerge concerning pre-mRNA processing from both old and newer experiments. The RNAPII complex is involved with pre-mRNA processing through binding of processing proteins to the CTD (carboxyl terminal domain) of the largest RNAPII subunit.
James E. Darnell was awarded the National Medal of Science for his seminal scientific discoveries related to gene expression in animal cells, including pathways of RNA processing and signal transduction from the cell surface to genes in the nucleus, and for his contributions as a scientific educator.
James E. Darnell's 179 research works with 33,802 citations and 31,835 reads, including: The JAK-STAT pathway at 30: Much learned, much more to do
Jim Darnell was born in Columbus, Mississippi - an impoverished region near the Alabama border - on September 9, 1930. His mother was a dietician, and young Jim saw medicine as a way to get out of the South.
