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  1. The Ankle Injury Management (AIM) trial: the way forward or off target? Bone Joint J. 2019 Dec;101-B(12):1466-1468. doi: 10.1302/0301-620X.101B12.BJJ-2019-0901. Authors Arul Ramasamy 1 2 , Joel Humphrey 2 3 , A H N Robinson 3 4 Affiliations 1 Royal British Legion Centre for Blast Injuries, Imperial ...

  2. the AIM trial Joel M Kremer, 1 Anthony S Russell,2 Paul Emery,3,4 Carlos Abud-Mendoza,5 Jacek Szechinski,6 Rene Westhovens,7 Tracy Li,8 Xianhuang Zhou,8 Jean-Claude Becker,8 Richard Aranda,8 Charles Peterfy,9 Harry K Genant10 22_annrheumdis139345.indd 1826 8/31/2011 10:01:16 PM

  3. The Ankle Injury Management (AIM) trial was a pragmatic equivalence randomized controlled trial conducted at 24 hospitals in the United Kingdom that recruited 620 patients aged more than 60 years with an unstable ankle fracture. The trial compared the usual care pathway of early management with open reduction and internal fixation with initially attempting non-surgical management using close ...

  4. 29 de may. de 2019 · Of the seven trials that were excluded, four were open label and not placebo-controlled, two were randomized but not placebo-controlled, ... AIM (NCT00048568) 4: Inadequate response to MTX: IV ABA or PBO; +bg MTX: 12: 433: 219: IM101100 (NCT00162266) 3: Inadequate response to MTX: IV ABA or PBO; +bg MTX: 12: 220: 119:

  5. 5 de mar. de 2022 · Methods. HI AIM (NCT04263467) is a randomized controlled trial (70 patients, 1:1) for patients with non-small cell lung cancer.Patients in the treatment arm, receive an exercise-intervention consisting of supervised and group-based exercise training, comprising primarily intermediate to high intensity interval training three times per week over 6 weeks.

  6. David J Keene,1* Dipesh Mistry,2 Julian Nam,3 Elizabeth Tutton,1,4 Robert Handley,5 Lesley Morgan,1 Emma Roberts,1 Bridget Gray,1 Andrew Briggs,3 Ranjit Lall,2 Tim JS Chesser,6 Ian Pallister,7 Sarah E Lamb1,2 and Keith Willett1 on behalf of the AIM trial group 1Kadoorie Centre for Critical Care Research and Education, John Radcliffe

  7. 5 de mar. de 2024 · A Phase 1 clinical trial is the first phase of three or four phases of research studies used to test a new treatment on humans. The major goal of a clinical trial is to determine whether a drug or procedure is safe for human use. Prior to phase 1 clinical trials, a drug must be studied extensively on disease cells in the laboratory and/or in ...