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22 de abr. de 2022 · Phylogenies (evolutionary trees) have provided key insights into the international spread of SARS-CoV-2 and enabled investigation of individual outbreaks and transmission chains in specific...
18 de may. de 2020 · An accurate phylogenetic tree underpins our understanding of the major transitions in evolution, such as the emergence of new body plans or metabolism, and is key to inferring the origin of new...
Genes, Genealogies and Phylogenies. Controversy over human evolution remains widespread. However, the Human Genome Project and genetic sequencing of many other species have provided myriad precise and unambiguous genetic markers that establish our evolutionary relationships with other mammals.
10 de ago. de 2022 · Complete genomes reveal the full gene repertoire of an organism. Using fully sequenced genomes for orthology inference allows for a more confident assessment of gene histories by improving the detection of orthology and paralogy relationships, the estimation of gene gains and losses, and the detection of horizontal transfer events ...
3 de feb. de 2020 · Introduction. The reconstruction of organismal evolutionary history using phylogenetics is a fundamental method applied to many areas of biology. Single nucleotide polymorphisms (SNPs), one of...
New phylogenetic methods have been developed with the explicit goal of linking genes and even specific mutations to species differences (‘PhyloG2P’). Applications of these methods show great promise for uncovering new sources of functional variation and tackling traits beyond the reach of traditional genetic approaches.
16 de dic. de 2019 · It comprises several areas of research at the interface between molecular and evolutionary biology and has two major goals: (i) to infer phylogenetic relationships between taxa and gain insights into the mechanisms of molecular evolution; and (ii) to use multispecies phylogenetic comparisons to infer putative functions for DNA or protein sequences.
