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Single-cell sequencing examines the nucleic acid sequence information from individual cells with optimized next-generation sequencing technologies, providing a higher resolution of cellular differences and a better understanding of the function of an individual cell in the context of its microenvironment. [1]
La secuenciación de células individuales (single-cell sequencing en inglés) es un conjunto de tecnologías utilizadas para determinar el orden de los nucleótidos en el ADN o ARN de células individuales.
15 de sept. de 2020 · Here, we review single-cell sequencing techniques for individual and multiomics profiling in single cells. We mainly describe single-cell genomic, epigenomic, and transcriptomic methods,...
25 de ene. de 2016 · Single-cell genome sequencing can provide detailed insights into the composition of single genomes that are not readily apparent when studying bulk cell populations.
26 de jun. de 2019 · This review introduces the latest advances in single-cell sequencing technologies and their applications in oncology, microbiology, neurology, reproduction, immunology, digestive and urinary systems, highlighting the important role that single-cell sequencing techniques play in these areas.
Since its introduction, single-cell RNA sequencing (scRNA-seq) approaches have revolutionized the genomics field as they created unprecedented opportunities for resolving cell heterogeneity by exploring gene expression profiles at a single-cell resolution.
31 de mar. de 2023 · Single-cell RNA sequencing (scRNA-seq) technologies have revolutionized molecular biology by enabling the measurement of transcriptome profiles at unprecedented scale and resolution.
