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1. www.ncbi.nlm.nih.gov › pmc › articlesAnthrax lethal toxin and tumor necrosis factor-α synergize on ...

   www.ncbi.nlm.nih.gov › pmc › articles

   19 de oct. de 2023 · Co-treatment of sub-lethal dose of LT and TNF induces intestinal tissue damage and mouse death. Anthrax-caused lethality in B6 mice requires the LT secreted from B.anthracis bacteria, although the lethal mechanism is independent of NLRP1B cleavage (Boyden and Dietrich 2006; Chui et al., 2019; Mitchell et al., 2019; Moayeri et al., 2010; Sandstrom et al., 2019; Terra et al., 2010).

2. edition.cnn.com › 2024/05/05 › usLessons from the deadly anthrax attacks of 2001 | CNN

   edition.cnn.com › 2024/05/05 › us

   • En caché

   5 de may. de 2024 · It floated through the air like a deadly lottery ticket where the unlucky person who chose to take a breath while passing by. It was killing people, one at a time, day by day. Between October 5 ...

3. pubmed.ncbi.nlm.nih.gov › 37855658Anthrax lethal toxin and tumor necrosis factor-α synergize on ......

   pubmed.ncbi.nlm.nih.gov › 37855658

   1 de feb. de 2024 · Bacillus anthracis lethal toxin (LT) is a determinant of lethal anthrax. Its function in myeloid cells is required for bacterial dissemination, and LT itself can directly trigger dysfunction of the cardiovascular system. The interplay between LT and the host responses is important in the pathogenesi …

4. www.ncbi.nlm.nih.gov › books › NBK190044Antibiotics for Anthrax Postexposure Prophylaxis

   www.ncbi.nlm.nih.gov › books › NBK190044

   30 de sept. de 2011 · The symptoms, treatment, and prognosis for a person with anthrax—the disease caused by Bacillus anthracis—depend on how the disease was contracted: gastrointestinal anthrax is acquired through ingestion of contaminated (undercooked) meat from animals that have ingested naturally occurring spores from the ground; cutaneous anthrax requires physical contact with the spores or vegetative ...

5. pubmed.ncbi.nlm.nih.gov › 12224524Structure and function of anthrax toxin - PubMed

   pubmed.ncbi.nlm.nih.gov › 12224524

   Anthrax toxin is a binary A-B toxin comprised of protective antigen (PA) and two enzymatic moieties, edema factor (EF) and lethal factor (LF). In the presence of a host cell-surface receptor, PA can mediate the delivery of EF and LF from the extracellular milieu into the host cell cytosol to effect …

6. www.ncbi.nlm.nih.gov › pmc › articlesRecent developments in the understanding and use of anthrax...

   www.ncbi.nlm.nih.gov › pmc › articles

   The B. anthracis V770-NP1-R production strain secretes only low levels of anthrax toxin components edema factor and lethal factor in comparison to the PA ... Timeline of key activities and licensure changes for Anthrax Vaccine Adsorbed from 1955–2015. 1955–1959 – Field evaluation of a predecessor anthrax vaccine by Brachman et al. .

7. www.amboss.com › us › knowledgeAnthrax - Knowledge @ AMBOSS

   www.amboss.com › us › knowledge

   15 de dic. de 2023 · Anthrax infection is an occupational hazard for people who handle livestock and process potentially infected animal materials such as wool or meat. Pathophysiology. ... (lethal factor): a metalloprotease that destroys MAPKK (mitogen-activated protein . kinase. kinase; ) → .