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  1. SIB Swiss Institute of Bioinformatics offers a wide range of web-based tools and databases for various aspects of biology and medicine. Explore the SIB Resources portal to find and access the most relevant and reliable resources for your research needs.

    • About

      Expasy is the bioinformatics resource portal of the SIB...

    • Contact

      Contact - Expasy Helpdesk. If you have questions or comments...

    • Translate

      Nucleotide sequence to a protein sequence. BLAST sequence...

    • Compute pI/Mw

      Compute the theoretical pI (isoelectric point) and Mw...

    • PeptideCutter

      PeptideCutter predicts potential substrate cleavage sites,...

    • UniProtKB

      The UniProt Knowledgebase is a central hub for the...

    • UniProtKB/Swiss-Prot

      UniProtKB/Swiss-Prot is the expertly curated component of...

    • ProtParam

      Compute various physical and chemical parameters for a given...

  2. Translate tool. Translate is a tool which allows the translation of a nucleotide (DNA/RNA) sequence to a protein sequence.

  3. ProtParam is a tool that calculates various physical and chemical parameters for a protein sequence from UniProtKB or user input. The parameters include molecular weight, pI, amino acid composition, extinction coefficient, half-life, instability index, aliphatic index and GRAVY.

  4. Expasy is a web service that provides various tools for protein analysis. Compute pI/Mw tool allows you to calculate the theoretical isoelectric point and molecular weight of UniProtKB entries or user-entered sequences.

  5. Expasy provides access to over 160 databases and software tools for life science and clinical research, from genomics to medical chemistry. It offers a user-friendly search engine, up-to-date information and links to SIB activities and outreach material.

  6. PeptideMass is a tool that computes the masses of peptides generated by cleaving a protein sequence with a chosen enzyme. It also returns theoretical isoelectric point and mass values for the protein, and can highlight peptides with post-translational modifications, database conflicts, or variants.

  7. UniProtKB is a central hub for the collection of functional information on proteins with accurate, consistent and rich annotation. It consists of expert-curated and computationally annotated records, and is produced by the UniProt consortium and supported by the SIB Swiss Institute of Bioinformatics.

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