Search results
Jack Leonard Strominger (born August 7, 1925) is the Higgins Professor of Biochemistry at Harvard University, specializing in the structure and function of human histocompatibility proteins and their role in disease. He won the Albert Lasker Award for Basic Medical Research in 1995.
Jack Strominger, M.D. Immunology pioneer Jack Strominger investigates self-tolerance and the immunology of pregnancy. His lab specializes in the structure and function of human histocompatibility proteins and their roles in disease. Strominger entered Harvard in 1942, joined Harvard’s Navy V-12 program, and majored in psychology.
My laboratory is focused now on 3 main projects: The role of MHC proteins and of products of other disease susceptibility genes in human autoimmunity, including multiple sclerosis, diabetes, pemphigus vulgaris and ankylosing spondylitis.
6 de ene. de 2020 · The first annual lecture to honor Jack Strominger will be held Wednesday at 4 p.m. at Harvard Medical School in the Armenise Amphitheater, 210 Longwood Ave., Boston. Harvard biochemistry professor Jack Strominger is still working in his lab at 94 years old. He will retire and become emeritus in July.
Tolerance is a central theme. Our studies involve the mechanisms of tolerance, both in pregnancy and in multiple sclerosis or its murine analog, Experimental Acquired Encephalomyelitis. My laboratory is focused now on 3 main projects:
The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation. DR Madden, JC Gorga, JL Strominger, DC Wiley. Nature 353 (6342), 321-325. , 1991. 917. 1991. The three-dimensional structure of HLA-B27 at 2.1 Å resolution suggests a general mechanism for tight peptide binding to MHC.
Jack L Strominger 1. Affiliation. 1 Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts 02138, USA. jlstrom@fas.harvard.edu. PMID: 16551242. DOI: 10.1146/annurev.immunol.24.021605.090703. Abstract.
