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  1. Hace 3 días · Chemodynamic therapy (CDT) presents promise as a cancer treatment method, but its efficacy faces challenges due to the inefficient Fenton catalytic reaction, where the transition metals' conversion from high to low valence states acts as the rate-limiting step.

  2. Hace 4 días · Modern chemotherapies offer a broad approach to cancer treatment but eliminate both cancer and non-cancer cells indiscriminately and, thus, are associated with a host of side effects. Advances in precision oncology have brought about new targeted therapeutics, albeit mostly limited to a subset of patients with an actionable mutation. They too come with side effects and, ultimately, ‘self ...

  3. Hace 4 días · Barrett’s esophagus (BE) is a precancerous condition that has the potential to develop into esophageal cancer (EC). Currently, there is a wide range of management options available for individuals at different pathological stages in Barrett’s esophagus (BE). However, there is currently a lack of knowledge regarding their comparative efficacy.

  4. Hace 4 días · For complete ablation of BE with low-grade dysplasia, high-grade dysplasia, or esophageal cancer, photodynamic therapy (PDT) had the highest SUCRA value of 94.1%, indicating it as the best regimen.

  5. Hace 2 días · It is demonstrated that the TOP CAR with TMIGD2 costimulation offered distinct benefits from CD28.41BB costimulation and is effective against solid tumors. Chimeric antigen receptor (CAR)–T cell therapy shows impressive efficacy treating hematologic malignancies but requires further optimization in solid tumors. Here, we developed a TMIGD2 optimized potent/persistent (TOP) CAR that ...

  6. Hace 4 días · There is still much progress to be made in understanding the underlying mechanisms of brain metastasis development and its optimal therapy in non–small cell lung cancer (NSCLC); it is very important to expand research in this area because brain metastasis strongly affects patients' quality of life and overall survival.

  7. Hi! My best friend’s mother has cancer (for the second time now) and she stopped doing chemo in november. Instead, she’s been doing this gerson therapy. Basically you have to drink a self-made smoothie every hour (strictly only vegetables and fruits) and do 3 coffee enemas every day. This is supposed to help detox your guts and liver.

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