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Hace 4 días · Collection of genomic data. The genome sequences of all strains of M. tuberculosis currently in existence, along with their corresponding proteomes, were obtained from the PATRIC database ...
Hace 2 días · We used CLC Genomics Workbench (v20.0.4) for adapter trimming and generation of de novo assemblies and annotated assembled genomes with Rapid Annotations (Subsystems Technology tool kit (RASTtk) accessed through PATRIC (v3.6.12). 93 To determine the molecular mechanisms of escaping, we aligned escaper assemblies to the ancestral reference with Snapgene (v6.0.2).
Hace 4 días · The assembled genome was annotated to the reference genome (NC_009089) using Geneious Prime. Circos plot was generated using PATRIC web resources.[41,42] Genome sequence files were deposited to the NCBI Sequence Read Archive (SRA)_BioProject PRJNA896704 under accession numbers SRX18115370, SRX18115371 and SAMN32933800.
Hace 3 días · Background Tuberculosis (TB) represents a major global health challenge. Drug resistance in Mycobacterium tuberculosis (MTB) poses a substantial obstacle to effective TB treatment. Identifying genomic mutations in MTB isolates holds promise for unraveling the underlying mechanisms of drug resistance in this bacterium. Methods In this study, we investigated the roles of single nucleotide ...
Hace 3 días · As the data continues to expand, it is important to enable researchers to filter on data that they are interested in seeing. Genome and Feature groups are a...
Hace 3 días · Genomes were classified taxonomically using GTDB-Tk v.2.1.1 . All genomes were annotated using PATRIC v.3.6.3, which provides subsystem annotation . Genomes and reads have been deposited to NCBI with the accession number PRJNA932444. For phylogenomic reconstruction, reference genomes were obtained from BV-BRC .
Hace 4 días · Campylobacter jejuni subsp. jejuni is the major pathogen causing gastroenteritis in humans and other animals worldwide (1, 2). Zoonotic diseases account for more than 60% of infections between humans and animals (3). Though overwhelming genome data of Campylobacter isolates from humans and poultry are currently available, those from non-human primates (NHPs) are rare (2, 4). NHPs provide ...
